Radiation
Radiation is the process
of emitting energy as waves or particles. There are two types: non-ionizing
radiation and ionizing radiation. The last one is the radiation which
has enough energy to produce ions. If this type of radiation passes
trough the body, it can produce damage in DNA.
Measurement
Radiation is measured in
dose. The amount of energy absorbed per unit weight of the organ or
tissue is called Absorbed Dose. Its unit
is Gray (Gy). One Gray is equivalent to one joule radiation energy absorbed
per kilogram of organ or tissue weight.
Equal doses of all types
of ionizing radiation are not equally harmful. For example, alpha particles
produce greater harm than beta particles and gamma and X-rays for a
given absorbed dose. That's why we express radiation dose as Equivalent
Dose that is equal to "absorbed dose" multiplied by
a "radiation weighting factor" (Wr). Its expressed in units
of Silverts(Sv) or rem. 1 rem=10 mSv.
Some parts of the body
are more sensitive than others. We define Effective
Dose the sum of the product of the equivalent dose and the tissue
weighting factor. The tissue weighting factor represents relative sensitivity
of organs for developing cancer. Its units is also the Silverts or rem.
Effective dose=sum of
[equivalent dose * tissue weighting factor]
The total effective dose
allowed in a period of five years is 100 mSv, however, in a year the
effective dose cannot be greater than 50 mSv.
The effects
The radiation effects on
a cell are random. That is, the same Equivalent Dose could strike the
cell many times and have different effects, including no effect, each
time. However, the more radiation that strikes the same cell, the greater
the chances of occurring a harmful effect.
There are four possible
effects when some radiation is absorbed by the cell:
- The cell may suffer
enough damage to cause loss of proper function, and the cell will
die.
- The cell may lose its
ability to reproduce.
- The cell’s genetic
code (DNA) may be damaged, and the future copies of the cell could
be altered, and result in a cancerous growth.
- No adverse effect.
Cells are made up of molecules.
Cell damage may be caused by interaction of radiation with these molecules.
Some cells are more likely to be affected by radiation than others,
for example, cells that multiply rapidly are the most susceptible. That
is why cells can often repair radiation damage, but if the cell multiplies
before it has had time to repair the most recent radiation damage, the
new cell might not be accurate copies of the old one.